Producer and supplier of pure, laboratory, special, pharmaceutical and technical chemicals
PENTA
  • Producer and supplier of pure, laboratory, special, pharmaceutical and technical chemicals

  • Producer and supplier of pure, laboratory, special, pharmaceutical and technical chemicals

  • Producer and supplier of pure, laboratory, special, pharmaceutical and technical chemicals

  • Producer and supplier of pure, laboratory, special, pharmaceutical and technical chemicals

  • Producer and supplier of pure, laboratory, special, pharmaceutical and technical chemicals

  • Producer and supplier of pure, laboratory, special, pharmaceutical and technical chemicals

  • 1
  • 2
  • 3
  • 4
  • 5
  • 6


Dangerous properties of chemicals

Manipulation with chemical substances and products requires paying attention to the warning symbols indicating potential hazards, to phrases defining specific risks and to instructions considering safe handling of such material.

Manipulation with chemical substances and products involves a broad spectrum of activities such as production, distribution (import, export), packaging, labelling and transport of this kind of goods. Most chemical substances show one or more hazardous properties.

There are some substances and products which we offer our customers, classified as Flammable (R 10), Harmful to Health (Xn), Irritating (Xi), and Sensitizing (R 42, R 43), and also substances and products that are not classified as hazardous.

When purchasing substances and products classified as Explosive (E), Oxidizing (O), Extremely Flammable (F+), Highly Flammable (F), Highly Toxic (T+), Toxic (T), Corrosive (C), Carcinogenic (R 45, R 46), Mutagenic (R 46), Toxic for Reproduction (R 60, R 61), and Dangerous for the Environment (N or R 52, R 53) customer have to declare that material will be handled only by qualified person.

Pharmaceutical materials and medical substances can be sold only to customers authorized for pharmaceuticals, i.e.to entities involved in healthcare and to legal entities that have their Good Distribution or Manufacturing practice certified by the State Institute for Drug Control (SIDC) - refer to Act No.79/1997, on Drugs and Pharmaceuticals. Chemicals in a quality meeting the current Czech Pharmacopoeia or European Pharmacopeia are provided only with test certificates of their manufacturers (without the certificates from SIDC).

General characteristics of a dangerous products are described in the MSDS (Material Safety Data Sheet), which the customer obtains gratis (either in printed or electronic version) with the first delivery or on request. MSDS consists of identification data from original producer of the dangerous substance. The MSDS´s content complies with the Czech and EU law as well as the current state of knowledge. It can serve as general advice how to safely operate with the dangerous substance, allows adopting arrangements considering health preservation and work safety as well as environmental risks.

Until 12/01/2010 the chemicals should be classified, labeled and packaged according to Directive 67/548/EEC incorporated into Act No. 356/2003 Coll. on chemical substances and chemical preparations and amending some laws as amended by subsequent regulations, as stipulated in the existing system. From December 1, 2010 the chemicals will be a labelled and packaged, according to Regulation 1272/2008/ES - CLP. Until December 1, 2012 both systems of the substances classification will be practicable.


I. The current classification in accordance with 67/548/EEC on chemical substances and chemical preparations and amending some Acts as amended by subsequent regulations:


  1. Explosive (labelled with the letter E), which may react exothermically even without the presence of air oxygen, whereby a gas is generated quickly, or which can under specific test conditions explode and burn up rapidly, or which can explode when warmed, if placed in a partially closed container,
  2. Oxidizing (labelled with the letter O), which initiate a highly exothermic reaction in contact with other substances, in particular flammable substances,
  3. Extremely flammable (labelled with the letter F+), which in their liquid state have a flash point below 0°C and the boiling point below 35°C, or which are in their gaseous state in flammable in contact with the air at a normal (room) temperature and at normal (atmospheric) pressure,
  4. Highly flammable (labelled with the letter F), which:
    • May warm up by themselves and then ignite in contact with the air at normal (room) temperature and normal (atmospheric) pressure, and without any supplied energy,
    • May in their solid state easily in. Flame after a short contact with a source of ignition, and which then continue to burn or smoulder even if the source of ignition has been removed,
    • In their liquid state have the flash point below 21°C and are not extremely flammable,
    • When in contact with water or a humid air release highly flammable gases at the minimum rate of 1 liter.kg-1.h-1,
  5. Flammable (labelled with phrase R10), which have their flash point between 21°C and 55°C,
  6. Highly toxic (labelled with the letter T+), which after inhalation, ingestion, or skin penetration, even in a very small quantity, may cause acute or chronic harm to human health, or even death,
  7. Toxic (labelled with the letter T), which after inhalation, ingestion, or skin penetration, even in a small quantity, may cause acute or chronic harm to human health, or even death,
  8. Harmful to health (labelled with the letters Xn), which after inhalation, ingestion, or skin penetration may cause acute or chronic harm to human health, or even death,
  9. Corrosive (labelled with the letter C), which after contact with living tissue may cause its destruction
  10. Irritating (labelled with the letters Xi), which do not have caustic properties yet they may cause a tissue inflammation after instant, long-term, or repeated contact with the skin or mucous membrane,
  11. Sensitizing (labelled with Phrases R42, R43), which after inhalation or skin penetration may cause excessive sensitivity, and following another exposure to the substance characteristic symptoms occur,
  12. Carcinogenic (labelled with Phrases R45, R49), which after inhalation, ingestion, or skin penetration may cause or increase the occurrence frequency of cancer,
  13. Mutagenic (labelled with Phrase R46), which after inhalation, ingestion, or skin penetration may cause or increase the occurrence frequency of genetic impairment,
  14. Toxic for reproduction (labelled with Phrases R60, R61), which after inhalation, ingestion, or skin penetration may cause or increase the occurrence frequency of non-hereditary impairment of descendants, impair reproduction functions or the ability of a man or woman to reproduce,
  15. Dangerous for the environment (labelled with the letter N or Phrases R52, R53, R59), which after dispersion in the environment represent or may represent an immediate or delayed danger.

The hazardous character of chemicals is defined by R Phrases, or by their combinations stated below.
Instructions for the safe handling of hazardous chemicals are defined with S Phrases, or with their combinations stated below.

Graphical representation of the hazard symbols
E
Explosive
Explosive
F+
Extremely flammable
Extremely flammable
T+
Very toxic
Very toxic
C
Corrosive
Corrosive
Xi
Irritant
Irritant
O
Oxidizing agent
Oxidizing agent
F
Highly flammable
Highly flammable
T
Toxic
Toxic
Xn
Harmful
Harmful
N
Dangerous for the environment
Dangerous for the environment





II. Classification according to the Regulation of the European Parliament and Council Regulation (EC) No 1272/2008 as amended:


Compared to the previous classification system, the Directive 67/548/EEC, the new regulation brings new changes and some extensions. According to this regulation the extension of dangerous physical properties occurred.

For the purpose of this Regulation, the following definitions shall apply:
  • "hazard pictogram" means a graphical composition that includes a symbol plus other graphic elements, such as a border, background pattern or colour that is intended to convey specific information on the hazard concerned;
  • "signal word" means a word that indicates the relative level of severity of hazards to alert the reader to a potential hazard; the following two levels are distinguished:
    • "Danger" means a signal word indicating the more severe hazard categories;
    • "Warning" means a signal word indicating the less severe hazard categories;
  • "hazard statement" means a phrase assigned to a hazard class and category that describes the nature of the hazards of a hazardous substance or mixture, including, where appropriate, the degree of hazard;
  • "precautionary statement" means a phrase that describes recommended measure(s) to minimise or prevent adverse effects resulting from exposure to a hazardous substance or mixture due to its use or disposal;


The hazard pictograms, character of hazards of chemicals and instructions for safe handling of hazardous chemicals are listed in the following tables.

PHYSICAL HAZARDS
Symbol: exploding bomb Symbol: exploding bomb Unstable explosives
Explosives of Divisions 1.1, 1.2, 1.3, 1.4
Self reactive substances and mixtures, Types A, B
Organic peroxides, Types A, B
Symbol: flame Symbol: flame Flammable gases, hazard category 1
Flammable aerosols, hazard categories 1, 2
Flammable liquids, hazard categories 1, 2, 3
Flammable solids, hazard categories 1, 2
Self-reactive substances and mixtures, Types B, C, D, E, F
Pyrophoric liquids, hazard category 1
Pyrophoric solids, hazard category 1
Self-heating substances and mixtures, hazard categories 1, 2
Substances and mixtures, which in contact with water, emit flammable gases, hazard categories 1, 2, 3
Organic peroxides, Types B, C, D, E, F
Symbol: flame over circle Symbol: flame over circle Oxidising gases, hazard category 1
Oxidising liquids, hazard categories 1, 2, 3
Oxidising solids, hazard categories 1, 2, 3
Symbol: gas cylinder Symbol: gas cylinder Gases under pressure:
Compressed gases;
Liquefied gases;
Refrigerated liquefied gases;
Dissolved gases.
Symbol: corrosion Symbol: corrosion Corrosive to metals, hazard category 1

 
HEALTH HAZARDS
Symbol: skull and crossbones Symbol: skull and crossbones Acute toxicity (oral, dermal, inhalation), hazard categories 1, 2, 3
Symbol: corrosion Symbol: corrosion Skin corrosion, hazard categories 1A, 1B, 1C
Serious eye damage, hazard category 1
Symbol: exclamation mark Symbol: exclamation mark Acute toxicity (oral, dermal, inhalation), hazard category 4
Skin irritation, hazard category 2
Eye irritation, hazard category 2
Skin sensitisation, hazard category 1
Specific Target Organ Toxicity - Single exposure, hazard category 3
Respiratory tract irritation
Narcotic effects
Symbol: health hazard Symbol: health hazard Respiratory sensitisation, hazard category 1
Germ cell mutagenicity, hazard categories 1A, 1B, 2
Carcinogenicity, hazard categories 1A, 1B, 2
Reproductive toxicity, hazard categories 1A, 1B, 2
Specific Target Organ Toxicity - Single exposure, hazard categories 1, 2
Specific Target Organ Toxicity - Repeated exposure, hazard categories 1, 2
Aspiration hazard, hazard category 1

 
ENVIRONMENTAL HAZARDS
Symbol: environment Symbol: environment Hazardous to the aquatic environment
- Acute hazard category 1
- Chronic hazard categories 1, 2

 
A pictogram is not required for the following classes and hazard categories:
  • physical hazard classes and hazard categories:
    Explosives of Division 1.5
    Explosives of Division 1.6
    Flammable gases, hazard Category 2
    Self-reactive substances and mixtures, Type G
    Organic peroxides, Type G
  • health hazard categories:
    Reproductive toxicity, Effects on or via lactation, additional hazard category
  • environmental hazard classes and hazard categories:
    Hazardous to the aquatic environment - Chronic hazard categories 3, 4




Search for products